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Drugs that inhibit CYP2D6 exercise, like paroxetine and quinidine, could lead to lowered clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Read the Medication Manual furnished by your pharmacist Befor